This write-up provides a comprehensive structure for a modern PowerPoint presentation on Wilms tumor (nephroblastoma), based on clinical resources like the Mayo Clinic StatPearls (NIH) 1. Introduction & Epidemiology Definition
Introduction
Epidemiology
- Incidence: ~1 in 10,000 children (varies by region).
- Peak age: 2–5 years.
- Sex: Slight female predominance or equal sex distribution depending on series.
- Associations: Higher risk in children with congenital anomalies or syndromes (e.g., WAGR, Denys–Drash, Beckwith–Wiedemann).
Slide 15: References and Resources
- COG AREN0532, AREN0533, AREN0534 (2006–2025 updates).
- SIOP-RTSG 2016 and 2025 Umbrella Protocol.
- National Wilms Tumor Study (NWTS-5) final report.
- Children’s Oncology Group Long-Term Follow-Up Guidelines v5.0.
With this content, your presentation will not only be “new” but truly cutting-edge — suitable for a pediatric oncology fellowship lecture or a national conference update.
For a fresh and engaging PowerPoint presentation on Wilms tumor (nephroblastoma), focus on the "Rule of 10s" and recent advancements in molecular risk stratification. Wilms tumor is the most common kidney cancer in children, typically diagnosed between ages 3 and 5. 1. The "Rule of 10s" for Clinical Presentation
New survivorship care plan: All patients should have an electronic survivorship passport with lifetime recommendations.
Stage II: Extends beyond the kidney but is completely excised.
Use visuals: ultrasound images, CT coronal sections, intraoperative photos, and treatment algorithm flowcharts. Keep text minimal – let the images and tables drive the learning.