It looks like you’re referring to a document or tool called "usbutil v2.2 rev1.0 en" — likely a USB utility (perhaps for firmware flashing, low-level formatting, or device management), with "en" indicating the English version.
Since many legendary titles—like God of War II or Final Fantasy X—were much larger than 4GB, they simply couldn't be copied onto a thumb drive as a single file. The Hero: ISEKO usbutil v2.2 rev1.0 en
Introduction
Open USBUtil: Run the USBUtil v2.2 rev1.0.exe as an Administrator. Select Source: Go to File > Create game from ISO. Choose Directories: Source: Select the folder containing your PS2 ISOs. Destination: Select the root of your USB drive. It looks like you’re referring to a document
Includes "IOPRP" and "DNAS" patching to help older games run from USB. Interface: Is the UI clear and modern, or old/dialog-based
It is widely remembered as the "classic" tool for creating the specific file structures required by the PS2’s USB gaming ecosystem.