Pharmacology is the bedrock of modern medicine. It is the science of how drugs interact with biological systems—specifically, what a drug does to the body (pharmacodynamics, or PD) and what the body does to the drug (pharmacokinetics, or PK). Without pharmacology, drug discovery would be random screening, and drug development would lack a rational framework for safety and efficacy. This write-up outlines how pharmacology guides every stage of the journey from a molecule to a marketed medicine.
—pharmacology acts as the primary compass, guiding a molecule from a laboratory "hit" to a marketed treatment. 1. The Core Pillars: PK and PD pharmacology in drug discovery and development
By the time a drug reaches Phase I clinical trials, the chemists have finished their job. But the pharmacologists are just getting busy. The Indispensable Role of Pharmacology in Drug Discovery
Pharmacology in Drug Discovery and Development: The Critical Path to New Therapeutics This write-up outlines how pharmacology guides every stage